The effects of a multifunctional oligomer and its incorporation strategies on the gene delivery efficiency of poly(l-lysine)Electronic supplementary information (ESI) available. See DOI: 10.1039/c2cc31359f

A novel multifunctional oligomer is synthesized and incorporated to enhance the gene delivery efficiency of PLL via non-electrostatic assembly and covalent grafting strategies. The improvement of the gene delivery efficiency is dependent on the gene carrying complex properties, and the properties ar...

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Bibliographic Details
Main Authors Zhou, Dezhong, Li, Congxin, Hu, Yuling, Zhou, Hao, Chen, Jiatong, Zhang, Zhengpu, Guo, Tianying
Format Journal Article
LanguageEnglish
Published 11.04.2012
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Summary:A novel multifunctional oligomer is synthesized and incorporated to enhance the gene delivery efficiency of PLL via non-electrostatic assembly and covalent grafting strategies. The improvement of the gene delivery efficiency is dependent on the gene carrying complex properties, and the properties are dependent on the oligomer incorporation strategy. The incorporation strategies of P(His- co -DMAEL) have obviously different effects on the properties of complexes.
Bibliography:Electronic supplementary information (ESI) available. See DOI
10.1039/c2cc31359f
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc31359f