Catalysis in flow: Au-catalysed alkylation of amines by alcoholsElectronic supplementary information (ESI) available: details of kinetic analysis and fitted curves, pressure effects, Arrhenius plots, and 1H NMR spectra of products. See DOI: 10.1039/c1gc16118k

• Main Authors: Zotova, Natalia, Roberts, Felicity J, Kelsall, Geoffrey H, Jessiman, Alan S, Hellgardt, Klaus, Hii, King Kuok (Mimi)
• Format: Journal Article
• Language: English
• Published: 01.01.2012

By using a greater reaction space afforded by a flow reactor, commercially available Au/TiO 2 can be used for highly selective direct alkylation of amines by alcohols, without the need for an inert atmosphere or base. A brief survey of substrates includes the alkylation of aromatic, aliphatic and ch...