Midbrain stimulation in freely behaving mice by photothermal transducers actuated via widefield near-infrared II light

• Published in: Nature biomedical engineering Vol. 6; no. 6; pp. 754 - 770
• Main Authors: Wu, Xiang, Jiang, Yuyan, Rommelfanger, Nicholas J., Yang, Fan, Zhou, Qi, Yin, Rongkang, Liu, Junlang, Cai, Sa, Ren, Wei, Shin, Andrew, Ong, Kyrstyn S., Pu, Kanyi, Hong, Guosong
• Format: Journal Article
• Language: English
• Published: 21.03.2022

Invasive brain implants and tethered optical fibres are typically used in restrained or motion-impaired animals, limiting the control and the decoding of the neural circuitry in freely behaving ones. Here we report the implant- and tether-free optical neurostimulation of deep brain regions by locall...