c-Myb coordinates survival and the expression of genes that are critical for the pre-BCR checkpoint1

• Published in: The Journal of immunology (1950) Vol. 200; no. 10; pp. 3450 - 3463
• Main Authors: Fahl, Shawn P., Daamen, Andrea R., Crittenden, Rowena B., Bender, Timothy P.
• Format: Journal Article
• Language: English
• Published: 13.04.2018

The c-Myb transcription factor is required for adult hematopoiesis, yet little is known about c-Myb function during lineage-specific differentiation due to the embryonic lethality of Myb -null mutations. We previously used tissue-specific inactivation of the murine Myb locus to demonstrate that c-My...