β1-Blockade Prevents Post-Ischemic Myocardial Decompensation Via Sphingosine-1 Phosphate Signaling
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| Published in | Journal of the American College of Cardiology Vol. 70; no. 2; pp. 182 - 192 |
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| Main Authors | , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
11.07.2017
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| Online Access | Get full text |
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| Author | Rapacciuolo, Antonio Rengo, Giuseppe Gao, Ehre Leosco, Dario Ferrara, Nicola George, Alvin J. Ibanez, Borja Gambino, Giuseppina Cannavo, Alessandro Liccardo, Daniela Paolocci, Nazareno Pun, Andres Koch, Walter J. |
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| AuthorAffiliation | c Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy i CIBER de enfermedades cardiovasculares, Madrid, Spain h IIS-Fundación Jiménez Díaz, Madid, Spain d Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain a Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania b Department of Translational Medical Science, University of Naples Federico II, Naples, Italy e Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy g Department of Experimental Medicine, University of Perugia, Perugia, Italy f Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland |
| AuthorAffiliation_xml | – name: a Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania – name: d Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain – name: f Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland – name: b Department of Translational Medical Science, University of Naples Federico II, Naples, Italy – name: h IIS-Fundación Jiménez Díaz, Madid, Spain – name: c Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy – name: g Department of Experimental Medicine, University of Perugia, Perugia, Italy – name: e Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy – name: i CIBER de enfermedades cardiovasculares, Madrid, Spain |
| Author_xml | – sequence: 1 givenname: Alessandro surname: Cannavo fullname: Cannavo, Alessandro organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 2 givenname: Giuseppe surname: Rengo fullname: Rengo, Giuseppe organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 3 givenname: Daniela surname: Liccardo fullname: Liccardo, Daniela organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 4 givenname: Andres surname: Pun fullname: Pun, Andres organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 5 givenname: Ehre surname: Gao fullname: Gao, Ehre organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 6 givenname: Alvin J. surname: George fullname: George, Alvin J. organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 7 givenname: Giuseppina surname: Gambino fullname: Gambino, Giuseppina organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 8 givenname: Antonio surname: Rapacciuolo fullname: Rapacciuolo, Antonio organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 9 givenname: Dario surname: Leosco fullname: Leosco, Dario organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 10 givenname: Borja surname: Ibanez fullname: Ibanez, Borja organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 11 givenname: Nicola surname: Ferrara fullname: Ferrara, Nicola organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 12 givenname: Nazareno surname: Paolocci fullname: Paolocci, Nazareno organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain – sequence: 13 givenname: Walter J. surname: Koch fullname: Koch, Walter J. organization: Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania Department of Translational Medical Science, University of Naples Federico II, Naples, Italy Istituti Clinici Scientifici Maugeri SpA Società Benefit, Telese Terme Institute, Italy Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain Department of Advanced Medical Science, University of Naples Federico II, Naples, Italy Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, Maryland Department of Experimental Medicine, University of Perugia, Perugia, Italy IIS-Fundación Jiménez Díaz, Madid, Spain CIBER de enfermedades cardiovasculares, Madrid, Spain |
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| Notes | Drs. Cannova and Rengo contributed equally to this work. |
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| Title | β1-Blockade Prevents Post-Ischemic Myocardial Decompensation Via Sphingosine-1 Phosphate Signaling |
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