Early Life Predictive Markers of Liver Disease Outcome in an International, Multi-Center Cohort of Children with Alagille Syndrome

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Bibliographic Details
Published inLiver international Vol. 36; no. 5; pp. 755 - 760
Main Authors Mouzaki, Marialena, Bass, Lee M., Sokol, Ronald J., Piccoli, David A., Quammie, Claudia, Loomes, Kathleen M., Heubi, James E., Hertel, Paula M., Scheenstra, Rene, Furuya, Katryn, Kutsch, Erika, Spinner, Nancy B., Robbins, Kristen N., Venkat, Veena, Rosenthal, Philip, Beyene, Joseph, Baker, Alastair, Kamath, Binita M.
Format Journal Article
LanguageEnglish
Published 18.08.2015
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Author Loomes, Kathleen M.
Piccoli, David A.
Kutsch, Erika
Furuya, Katryn
Spinner, Nancy B.
Robbins, Kristen N.
Scheenstra, Rene
Kamath, Binita M.
Bass, Lee M.
Heubi, James E.
Venkat, Veena
Baker, Alastair
Mouzaki, Marialena
Beyene, Joseph
Hertel, Paula M.
Sokol, Ronald J.
Quammie, Claudia
Rosenthal, Philip
AuthorAffiliation 5 Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati
11 Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco
12 Clinical Epidemiology & Biostatistics, McMaster University, Hamilton
1 Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto
6 Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas
3 Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado
13 King’s Paediatric Liver Centre, King’s College Hospital, London UK
2 Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago
9 Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia
10 Division
AuthorAffiliation_xml – name: 12 Clinical Epidemiology & Biostatistics, McMaster University, Hamilton
– name: 1 Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto
– name: 5 Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati
– name: 8 Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware
– name: 9 Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia
– name: 3 Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado
– name: 7 Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands
– name: 10 Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh
– name: 6 Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas
– name: 2 Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago
– name: 4 Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia
– name: 11 Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco
– name: 13 King’s Paediatric Liver Centre, King’s College Hospital, London UK
Author_xml – sequence: 1
  givenname: Marialena
  surname: Mouzaki
  fullname: Mouzaki, Marialena
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
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  givenname: Lee M.
  surname: Bass
  fullname: Bass, Lee M.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 3
  givenname: Ronald J.
  surname: Sokol
  fullname: Sokol, Ronald J.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 4
  givenname: David A.
  surname: Piccoli
  fullname: Piccoli, David A.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 5
  givenname: Claudia
  surname: Quammie
  fullname: Quammie, Claudia
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 6
  givenname: Kathleen M.
  surname: Loomes
  fullname: Loomes, Kathleen M.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 7
  givenname: James E.
  surname: Heubi
  fullname: Heubi, James E.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 8
  givenname: Paula M.
  surname: Hertel
  fullname: Hertel, Paula M.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 9
  givenname: Rene
  surname: Scheenstra
  fullname: Scheenstra, Rene
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 10
  givenname: Katryn
  surname: Furuya
  fullname: Furuya, Katryn
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 11
  givenname: Erika
  surname: Kutsch
  fullname: Kutsch, Erika
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 12
  givenname: Nancy B.
  surname: Spinner
  fullname: Spinner, Nancy B.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 13
  givenname: Kristen N.
  surname: Robbins
  fullname: Robbins, Kristen N.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 14
  givenname: Veena
  surname: Venkat
  fullname: Venkat, Veena
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 15
  givenname: Philip
  surname: Rosenthal
  fullname: Rosenthal, Philip
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 16
  givenname: Joseph
  surname: Beyene
  fullname: Beyene, Joseph
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 17
  givenname: Alastair
  surname: Baker
  fullname: Baker, Alastair
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
– sequence: 18
  givenname: Binita M.
  surname: Kamath
  fullname: Kamath, Binita M.
  organization: Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, University of Toronto Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago Division of Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital, Cincinnati Division of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas Division of Gastroenterology, Hepatology and Nutrition, Beatrix Children’s Hospital, University Medical Center, Groningen Netherlands Division of Gastroenterology, Hepatology and Nutrition, Nemours/AI. duPont Hospital for Children, Delaware Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Pittsburgh, Pittsburgh, University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition, UCSF Benioff Children’s Hospital, San Francisco Clinical Epidemiology & Biostatistics, McMaster University, Hamilton King’s Paediatric Liver Centre, King’s College Hospital, London UK
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DOI 10.1111/liv.12920
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Anatomy & Physiology
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Title Early Life Predictive Markers of Liver Disease Outcome in an International, Multi-Center Cohort of Children with Alagille Syndrome
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