Evolution of a MCM complex in flies promoting meiotic crossovers by blocking BLM helicase

Generation of meiotic crossovers in many eukaryotes requires the elimination of anti-crossover activities by utilizing the Msh4–Msh5 heterodimer to block helicases. Msh4 and Msh5 have been lost from the flies Drosophila and Glossina but we identified a complex of mini-chromosome maintenance (MCM) pr...

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Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 338; no. 6112; pp. 1363 - 1365
Main Authors Kohl, Kathryn P., Jones, Corbin D., Sekelsky, Jeff
Format Journal Article
LanguageEnglish
Published 07.12.2012
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