TASK-3 CHANNEL DELETION IN MICE RECAPITUATES LOW RENIN ESSENTIAL HYPERTENSION

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 59; no. 5; pp. 999 - 1005
• Main Authors: Guagliardo, Nick A, Yao, Junlan, Hu, Changlong, Schertz, Elaine M, Tyson, David A, Carey, Robert M, Bayliss, Douglas A, Barrett, Paula Q
• Format: Journal Article
• Language: English
• Published: 09.04.2012

Idiopathic primary hyperaldosteronism (IHA) and low-renin essential hypertension (LREH) are common forms of hypertension, characterized by an elevated aldosterone-renin ratio (ARR) and hypersensitivity to Angiotensin II (Ang II). They are suggested to be two states within a disease spectrum that pro...