Aneuploidy and polyploidy underlie adaptive evolution of yeast cells deprived of a conserved cytokinesis motor

• Published in: Cell Vol. 135; no. 5; pp. 879 - 893
• Main Authors: Rancati, Giulia, Pavelka, Norman, Fleharty, Brian, Noll, Aaron, Allen, Rhonda, Walton, Kendra, Perera, Anoja, Staehling-Hampton, Karen, Seidel, Chris W., Li, Rong
• Format: Journal Article
• Language: English
• Published: 28.11.2008

The ability to evolve is a fundamental feature of biological systems, but the mechanisms underlying this capacity and the evolutionary dynamics of conserved core processes remain elusive. We show here that yeast cells deleted of MYO1 , encoding the only myosin-II normally required for cytokinesis, r...