A Phase II study of iodine-131 tositumomab plus chemotherapy in patients with previously untreated mantle cell lymphoma

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Published inClinical lymphoma, myeloma and leukemia Vol. 20; no. 11; pp. 749 - 756.e1
Main Authors Zelenetz, Andrew D., Popplewell, Leslie L., Noy, Ariela, Horner, Thierry J., Lin, Thomas S., Donnelly, Gerard, Sgouros, George, Rijo, Ivelise, Divgi, Chaitanya R.
Format Journal Article
LanguageEnglish
Published 29.04.2019
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Author Noy, Ariela
Lin, Thomas S.
Divgi, Chaitanya R.
Donnelly, Gerard
Sgouros, George
Rijo, Ivelise
Popplewell, Leslie L.
Zelenetz, Andrew D.
Horner, Thierry J.
AuthorAffiliation a Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA
b City of Hope Medical Center, Duarte, CA, USA
g Columbia University, New York, NY, USA
e North Shore University Hospital, New York, NY, USA
f Johns Hopkins Hospital, Baltimore, MD, USA
c Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA
d GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA
AuthorAffiliation_xml – name: a Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA
– name: b City of Hope Medical Center, Duarte, CA, USA
– name: d GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA
– name: e North Shore University Hospital, New York, NY, USA
– name: f Johns Hopkins Hospital, Baltimore, MD, USA
– name: c Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA
– name: g Columbia University, New York, NY, USA
Author_xml – sequence: 1
  givenname: Andrew D.
  surname: Zelenetz
  fullname: Zelenetz, Andrew D.
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
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  givenname: Leslie L.
  surname: Popplewell
  fullname: Popplewell, Leslie L.
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
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  givenname: Ariela
  surname: Noy
  fullname: Noy, Ariela
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
– sequence: 4
  givenname: Thierry J.
  surname: Horner
  fullname: Horner, Thierry J.
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
– sequence: 5
  givenname: Thomas S.
  surname: Lin
  fullname: Lin, Thomas S.
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
– sequence: 6
  givenname: Gerard
  surname: Donnelly
  fullname: Donnelly, Gerard
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
– sequence: 7
  givenname: George
  surname: Sgouros
  fullname: Sgouros, George
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
– sequence: 8
  givenname: Ivelise
  surname: Rijo
  fullname: Rijo, Ivelise
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
– sequence: 9
  givenname: Chaitanya R.
  surname: Divgi
  fullname: Divgi, Chaitanya R.
  organization: Memorial Sloan-Kettering Cancer Center, Division of Hematologic Oncology, Lymphoma Service, New York, NY, USA City of Hope Medical Center, Duarte, CA, USA Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell Medical Center, New York, NY, USA GlaxoSmithKline, Oncology Research and Development, Collegeville, PA, USA North Shore University Hospital, New York, NY, USA Johns Hopkins Hospital, Baltimore, MD, USA Columbia University, New York, NY, USA
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Notes ADZ was the Principle Investigator, designed the study and protocol, contributed to data collection, analysis and interpretation. AN, CRD, GS, GD, IR, and LLP contributed to protocol development and data acquisition. TJH, and TSL contributed to the study design and data analysis and interpretation. All authors were involved at each stage of manuscript preparation and approved the final version.
Current affiliation: Janssen, Scientific Affairs, Horsham, PA, USA
Current affiliation: NYU Perlmutter Cancer Center, Lake Success, NY, USA
Author contributions
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PublicationTitle Clinical lymphoma, myeloma and leukemia
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Title A Phase II study of iodine-131 tositumomab plus chemotherapy in patients with previously untreated mantle cell lymphoma
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