Novel recombinant R-spondin1 promotes hair regeneration by targeting the Wnt/β-catenin signaling pathway Recombinant R-spondin1 promotes hair regeneration

• Published in: Acta biochimica et biophysica Sinica Vol. 55; no. 8; pp. 1213 - 1221
• Main Authors: Chen, Yijun, Lu, Zhujin, Feng, Jiaxin, Chen, Zefeng, Liu, Zejian, Wang, Xiuqi, Yan, Huichao, Gao, Chunqi
• Format: Journal Article
• Language: English
• Published: Oxford University Press 20.07.2023

Roof plate-specific spondin 1 (R-spondin1, RSPO1) is a Wnt/β-catenin signaling pathway activator that binds with Wnt ligands to stimulate the Wnt/β-catenin signaling pathway, which is key to hair regeneration. However, it is not clear whether recombinant RSPO1 (rRSPO1) affects hair regeneration. Her...