Monitoring of pH and PCO2 in children using the Paratrend 7 in a peripheral vein

• Published in: Canadian journal of anesthesia Vol. 45; no. 1; p. 81
• Main Authors: Tobias, J D, Meyer, Jr, D J, Helikson, M A
• Format: Journal Article
• Language: English
• Published: United States 01.01.1998
• Subjects: Adolescent; Arteries; Bias; Carbon Dioxide - blood; Catheterization, Peripheral - instrumentation; Catheters, Indwelling; Child; Child, Preschool; Critical Care; Female; Humans; Hydrogen-Ion Concentration; Infant; Linear Models; Male; Monitoring, Physiologic - instrumentation; Prospective Studies; Respiratory Insufficiency - blood; Sensitivity and Specificity; Veins
• ISSN: 0832-610X

To determine the accuracy of the Paratrend 7 monitor inserted into a peripheral vein in providing continuous measurements of PCO2 and pH in children with respiratory failure. In a prospective, case series at a University based PICU in a tertiary referral hospital and following informed consent, the Paratrend 7 intra-arterial blood gas monitoring system was inserted through a peripheral intravenous cannula. When clinically indicated, an arterial blood gas (ABG) was obtained. The values of pH and PCO2 from the Paratrend 7 and the ABG were compared using linear regression analysis and Bland-Altman analysis. Seventeen ABGs were obtained in the 4 patients. PaCO2 ranged from 29 to 51 mmHg and the pH values from 7.16 to 7.50. Linear regression analysis for the: Paratrend 7 pH vs the ABG pH resulted in an r = 0.9678 and an r2 = 0.9367 (P < 0.0001). Linear regression analysis for the Paratrend 7 CO2 vs ABG CO2 resulted in an r = 0.8273 and an r2 = 0.6845 (P = 0.01). Using a Bland and Altman analysis, the bias +/- precision of the PCO2 values was 3 +/- 1.4 and 0.036 +/- 0.02 for the pH values. The pH and PCO2 values obtained from the Paratrend 7 monitor provide a clinically acceptable correlation with arterial values.