13 C-metabolic flux analysis reveals metabolic rewiring in HL-60 neutrophil-like cells through differentiation and immune stimulation

• Published in: Metabolic engineering communications Vol. 18; p. e00239
• Main Authors: Taniguchi, Takeo, Okahashi, Nobuyuki, Matsuda, Fumio
• Format: Journal Article
• Language: English
• Published: Netherlands 01.06.2024
• Subjects: Immune response; 13C-metabolic flux analysis; HL-60; Neutrophil; Differentiation

Neutrophils are innate immune cells and the first line of defense for the maintenance of homeostasis. However, our knowledge of the metabolic rewiring associated with their differentiation and immune stimulation is limited. Here, quantitative C-metabolic flux analysis was performed using HL-60 cells...