Respiratory viral infection promotes the awakening and outgrowth of dormant metastatic breast cancer cells in lungs

• Published in: Research square
• Main Authors: Chia, Shi B, Johnson, Bryan J, Hu, Junxiao, Vermeulen, Roel, Chadeau-Hyam, Marc, Guntoro, Fernando, Montgomery, Hugh, Boorgula, Meher Preethi, Sreeka, Varsha, Goodspeed, Andrew, Davenport, Bennett, Pereira, Felipe V, Zaberezhnyy, Vadym, Schleicher, Wolfgang E, Gao, Dexiang, Cadar, Andreia N, Papanicolaou, Michael, Beheshti, Afshin, Baylin, Stephen B, Costello, James, Bartley, Jenna M, Morrison, Thomas E, Aguirre-Ghiso, Julio A, Rincon, Mercedes, DeGregori, James
• Format: Journal Article
• Language: English
• Published: United States 05.04.2024

Breast cancer is the second most common cancer globally. Most deaths from breast cancer are due to metastatic disease which often follows long periods of clinical dormancy . Understanding the mechanisms that disrupt the quiescence of dormant disseminated cancer cells (DCC) is crucial for addressing...