Stalling of Transcription by Putative G-quadruplex Sequences and CRISPR-dCas9

Putative G-quadruplex forming sequences (PQS) have been identified in promoter sequences of prominent genes that are implicated among others in cancer and neurological disorders. We explored mechanistic aspects of CRISPR-dCas9-mediated gene expression regulation, which is transient and sequence spec...

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Bibliographic Details
Published inbioRxiv : the preprint server for biology
Main Authors Hoque, Mohammed Enamul, Kabir, Mohammad Lutful, Shiekh, Sajad, Balci, Hamza, Basu, Soumitra
Format Journal Article
LanguageEnglish
Published United States 17.03.2024
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