Sialyl Lewis X glycomimetics bearing an extended anionic chain targeting E- and P- selectin binding sites
Neutrophil binding to vascular P- and E-selectin is the rate-limiting step in the recruitment of immune cells to sites of inflammation. Many diseases, including sickle cell anemia, post-myocardial infarction reperfusion injury, and acute respiratory distress syndrome are characterized by dysregulate...
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Published in | Bioorganic & medicinal chemistry Vol. 98; p. 117553 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
15.01.2024
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Subjects | |
Online Access | Get full text |
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