Method for Depletion of Mitochondria DNA in Human Bronchial Epithelial Cells

• Published in: bioRxiv : the preprint server for biology
• Main Authors: Novotny, Michael V, Xu, Weiling, Mulya, Anny, Janocha, Allison J, Erzurum, Serpil C
• Format: Journal Article
• Language: English
• Published: United States 28.07.2023
• Subjects: ρ0 cells; bronchial epithelial cells BET-1A; mitochondrial DNA; BEAS-2B

Mitochondria are increasingly recognized to play a role in the airway inflammation of asthma. Model systems to study the role of mitochondrial gene expression in bronchial epithelium are lacking. Here, we create custom bronchial epithelial cell lines derived from primary airway epithelium that are d...