Emerging of a new CD3 + CD31 H CD184 + tang cell phenothype in Sjögren's syndrome induced by microencapsulated human umbilical cord matrix-derived multipotent stromal cells

• Published in: Frontiers in immunology Vol. 14; p. 1095768
• Main Authors: Montanucci, Pia, Bistoni, Onelia, Antonucci, Matteo, Pescara, Teresa, Greco, Alessia, Basta, Giuseppe, Bartoloni, Elena, Gerli, Roberto, Calafiore, Riccardo
• Format: Journal Article
• Language: English
• Published: Switzerland 2023
• Subjects: Autoimmune Diseases; Humans; Leukocytes, Mononuclear; Sjogren's Syndrome; Stromal Cells; Umbilical Cord; CD31; immunoprotection; angiogenetic T cells; Sjogren’ s syndrome; human multipotent stromal cells; B regulatory cells (B10)

Sjögren's syndrome (SS) is an autoimmune disease hallmarked by infiltration and destruction of exocrine glands. Currently, there is no therapy that warrants full recovery of the affected tissues. Umbilical cord-derived multipotent stromal cells, microincapsulated in an endotoxin-free alginate g...