PPy@Fe 3 O 4 nanoparticles inhibit the proliferation and metastasis of CRC via suppressing the NF-κB signaling pathway and promoting ferroptosis

• Published in: Frontiers in bioengineering and biotechnology Vol. 10; p. 1001994
• Main Authors: Yu, Zhilong, Tong, Shanshi, Wang, Chenyi, Wu, Zizhen, Ye, Yingjiang, Wang, Shan, Jiang, Kewei
• Format: Journal Article
• Language: English
• Published: Switzerland 2022
• Subjects: NF-κB; colorectal cancer; ferroptosis; nanoparticles; metastasis

Colorectal cancer (CRC) is one of the most common cancers of the digestive tract, and patients with advanced-stage cancer have poor survival despite the use of multidrug conventional chemotherapy regimens. Intra-tumor heterogeneity of cancerous cells is the main obstacle in the way to effective canc...