Muscle Protein Synthesis Following Protein Administration in Critical Illness

• Published in: American journal of respiratory and critical care medicine
• Main Authors: Chapple, Lee-Anne S, Kouw, Imre W K, Summers, Matthew J, Weinel, Luke M, Gluck, Samuel, Raith, Eamon, Slobodian, Peter, Soenen, Stijn, Deane, Adam M, van Loon, Luc J C, Chapman, Marianne J
• Format: Journal Article
• Language: English
• Published: United States 18.05.2022
• Subjects: anabolic resistance; enteral nutrition; muscle protein synthesis; critical illness; protein

Rationale Dietary protein may attenuate the muscle atrophy experienced by patients in the Intensive Care Unit (ICU), yet protein handling is poorly understood. Objective To quantify protein digestion and amino acid absorption, and fasting and postprandial myofibrillar protein synthesis during critic...