Pharmacological tools to mobilise mesenchymal stromal cells into the blood promote bone formation after surgery

• Published in: npj Regenerative medicine Vol. 5; no. 1; p. 3
• Main Authors: Fellous, Tariq G, Redpath, Andia N, Fleischer, Mackenzie M, Gandhi, Sapan, Hartner, Samantha E, Newton, Michael D, François, Moïra, Wong, Suet-Ping, Gowers, Kate H C, Fahs, Adam M, Possley, Daniel R, Bonnet, Dominique, Urquhart, Paula, Nicolaou, Anna, Baker, Kevin C, Rankin, Sara M
• Format: Journal Article
• Language: English
• Published: United States 21.02.2020

Therapeutic approaches requiring the intravenous injection of autologous or allogeneic mesenchymal stromal cells (MSCs) are currently being evaluated for treatment of a range of diseases, including orthopaedic injuries. An alternative approach would be to mobilise endogenous MSCs into the blood, the...