Longitudinal multicenter retrospective cohort study of treatment outcomes in extramammary Paget's disease

Extramammary Paget's disease (EMPD) is a rare, usually intraepithelial, cutaneous adenocarcinoma morphologically and histologically similar to mammary Paget's arising in areas outside of the lactiferous tissue. Management options include wide local excision (WLE) or Mohs surgery; radiother...

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Published inBritish journal of dermatology (1951)
Main Authors Liu, K X, Huang, V, Chen, C A, Elco, C P, Chen, S T, Stern, R S, Wu, P A
Format Journal Article
LanguageEnglish
Published England 06.02.2021
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Abstract Extramammary Paget's disease (EMPD) is a rare, usually intraepithelial, cutaneous adenocarcinoma morphologically and histologically similar to mammary Paget's arising in areas outside of the lactiferous tissue. Management options include wide local excision (WLE) or Mohs surgery; radiotherapy, photodynamic therapy, laser ablation, topical therapies, and systemic chemotherapy. Regardless of therapy, disease recurrence is common and problematic. While large database studies have examined mortality rates for various populations of EMPD patients; longitudinal experience of patients with EMPD, including treatment-free survival (TFS), remains not well-understood.
AbstractList Extramammary Paget's disease (EMPD) is a rare, usually intraepithelial, cutaneous adenocarcinoma morphologically and histologically similar to mammary Paget's arising in areas outside of the lactiferous tissue. Management options include wide local excision (WLE) or Mohs surgery; radiotherapy, photodynamic therapy, laser ablation, topical therapies, and systemic chemotherapy. Regardless of therapy, disease recurrence is common and problematic. While large database studies have examined mortality rates for various populations of EMPD patients; longitudinal experience of patients with EMPD, including treatment-free survival (TFS), remains not well-understood.
Author Elco, C P
Huang, V
Chen, C A
Chen, S T
Liu, K X
Stern, R S
Wu, P A
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  organization: Department of Dermatology, University of California San Francisco, San Francisco, California
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  surname: Chen
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  organization: Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts
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  orcidid: 0000-0002-8042-5257
  surname: Wu
  fullname: Wu, P A
  organization: Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts
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Snippet Extramammary Paget's disease (EMPD) is a rare, usually intraepithelial, cutaneous adenocarcinoma morphologically and histologically similar to mammary Paget's...
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Title Longitudinal multicenter retrospective cohort study of treatment outcomes in extramammary Paget's disease
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