Antibody to lipoid A in the treatment of septic shock

• Published in: Infection Vol. 15 Suppl 2; p. S89
• Main Authors: Jaspers, L, Marget, W, Mar, P J, Hoffmann, K, Langecker, P, Ruckdeschel, G, Obermeier, A, Kastenbauer, E
• Format: Journal Article
• Language: German
• Published: Germany 1987
• Subjects: Antibody Formation; Antitoxins - therapeutic use; Clinical Trials as Topic; Double-Blind Method; Humans; Immunoglobulin G - therapeutic use; Lipid A - immunology; Random Allocation; Shock, Septic - therapy

The protective effect of high-titer anti-lipid A hyperimmune globulin with respect to the course of the disease and the mortality rate was studied in patients with septicemia verified by positive blood cultures. Six patients were treated with anti-lipid A in an open study. Dramatic improvement in fe...