Intercellular Bridge Mediates Ca 2+ Signals between Micropatterned Cells via IP 3 and Ca 2+ Diffusion

• Published in: Biophysical journal Vol. 118; no. 5; p. 1196
• Main Authors: Xing, Fulin, Qu, Songyue, Liu, Junfang, Yang, Jianyu, Hu, Fen, Drevenšek-Olenik, Irena, Pan, Leiting, Xu, Jingjun
• Format: Journal Article
• Language: English
• Published: United States 10.03.2020
• Subjects: Calcium - metabolism; Calcium Signaling; Diffusion; Endoplasmic Reticulum - metabolism; Inositol 1,4,5-Trisphosphate - metabolism; Inositol 1,4,5-Trisphosphate Receptors - metabolism

Intercellular bridges are plasma continuities formed at the end of the cytokinesis process that facilitate intercellular mass transport between the two daughter cells. However, it remains largely unknown how the intercellular bridge mediates Ca communication between postmitotic cells. In this work,...