Elevated levels of periostin and TGF-β1 in the bronchoalveolar lavage fluid of patients with idiopathic eosinophilic pneumonia

• Published in: Asian Pacific journal of allergy and immunology
• Main Authors: Katoh, Shigeki, Matsumoto, Nobuhiro, Tanaka, Hitomi, Yasokawa, Naoya, Kittaka, Makoto, Kurose, Kouji, Abe, Masaaki, Yoshioka, Daisuke, Shirai, Ryo, Nakazato, Masamitsu, Kobashi, Yoshihiro
• Format: Journal Article
• Language: English
• Published: Thailand 23.04.2019

Periostin is induced in bronchial epithelial cells and fibroblasts by various stimuli including interleukin (IL)13 and transforming growth factor (TGF)-β1, and is involved in allergic diseases such as asthma and atopic dermatitis, playing an important role in tissue remodeling and fibrosis. The role...