Prevalence and associated factors of potentially inappropriate medications among Iranian older adults
Aim Potentially inappropriate medications (PIMs) in older people are associated with the increased use of health care services. The aim of this study was to investigate the prevalence of PIMs among the elderly being referred to pharmacies in Tehran using the Beers criteria of 2012, and identify fact...
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Published in | Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina Vol. 16; no. 1; p. 121 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Bosnia and Herzegovina
01.02.2019
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Abstract | Aim Potentially inappropriate medications (PIMs) in older people are associated with the increased use of health care services. The aim of this study was to investigate the prevalence of PIMs among the elderly being referred to pharmacies in Tehran using the Beers criteria of 2012, and identify factors related to PIMs. Methods This cross-sectional study was conducted on elderly patients (60 years and above) referred to pharmacies in Tehran, in 2017. The Beers' criteria 2012 were used to evaluate PIMs. The logistic regression analysis was used to find sociodemographic predictors of PIMs. Results The mean age of 1591 patients was 70.51 years. The overall prevalence of PIMs was 26.0%. The most frequent PIMs, in order of frequency, included diclofenac (13.5%), alprazolam (9.3%), and chlordiazepoxide (9.1%) and clonazepam (8.4%). The pain medications were found to be most common PIMs (37.6%). Polypharmacy (OR=3.64, CI 95%: .81-4.70; p<0.001), number of chronic disease (OR=2.371, CI 95%:1.71-3.28; p<0.001) insomnia (OR=1.45, CI 95%: 1.13-1.87; p<0.01) and type of specialists were found as PIMs risk factors. Internal medicine specialists prescribed PIMs significantly fewer times than other specialists(OR=0.59, CI 95%: 0.40-0.88; p<0.01, and the orthopedic specialists prescribed PIMs significantly more times than other physicians (OR=3.23, CI 95%: 5.76-1.81; p<0.001). Conclusion High prevalence of PIMs among Iranian elderly patients implies a need for the development and operationalization of scientific guidelines for the use of medicines. It is also necessary to hold training courses for physicians to be educated in such cases. |
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AbstractList | Aim Potentially inappropriate medications (PIMs) in older people are associated with the increased use of health care services. The aim of this study was to investigate the prevalence of PIMs among the elderly being referred to pharmacies in Tehran using the Beers criteria of 2012, and identify factors related to PIMs. Methods This cross-sectional study was conducted on elderly patients (60 years and above) referred to pharmacies in Tehran, in 2017. The Beers' criteria 2012 were used to evaluate PIMs. The logistic regression analysis was used to find sociodemographic predictors of PIMs. Results The mean age of 1591 patients was 70.51 years. The overall prevalence of PIMs was 26.0%. The most frequent PIMs, in order of frequency, included diclofenac (13.5%), alprazolam (9.3%), and chlordiazepoxide (9.1%) and clonazepam (8.4%). The pain medications were found to be most common PIMs (37.6%). Polypharmacy (OR=3.64, CI 95%: .81-4.70; p<0.001), number of chronic disease (OR=2.371, CI 95%:1.71-3.28; p<0.001) insomnia (OR=1.45, CI 95%: 1.13-1.87; p<0.01) and type of specialists were found as PIMs risk factors. Internal medicine specialists prescribed PIMs significantly fewer times than other specialists(OR=0.59, CI 95%: 0.40-0.88; p<0.01, and the orthopedic specialists prescribed PIMs significantly more times than other physicians (OR=3.23, CI 95%: 5.76-1.81; p<0.001). Conclusion High prevalence of PIMs among Iranian elderly patients implies a need for the development and operationalization of scientific guidelines for the use of medicines. It is also necessary to hold training courses for physicians to be educated in such cases. |
Author | Momtaz, Yadollah Abolfathi Saboor, Malihe Sahaf, Robab Kamrani, Ahmad-Ali Akbari |
Author_xml | – sequence: 1 givenname: Malihe surname: Saboor fullname: Saboor, Malihe organization: Iranian Research Centre on Ageing, University of Social Welfare and Rehabilitation Sciences Tehran, Iran – sequence: 2 givenname: Ahmad-Ali Akbari surname: Kamrani fullname: Kamrani, Ahmad-Ali Akbari organization: Iranian Research Centre on Ageing, University of Social Welfare and Rehabilitation Sciences Tehran, Iran – sequence: 3 givenname: Yadollah Abolfathi surname: Momtaz fullname: Momtaz, Yadollah Abolfathi organization: Iranian Research Centre on Ageing, University of Social Welfare and Rehabilitation Sciences Tehran, Iran, Malaysian Research Institute on Ageing (My Ageing), University Putra Malaysia, Serdang, Selangor, Malaysia – sequence: 4 givenname: Robab surname: Sahaf fullname: Sahaf, Robab organization: Iranian Research Centre on Ageing, University of Social Welfare and Rehabilitation Sciences Tehran, Iran |
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SubjectTerms | Age Factors Aged Aged, 80 and over Analgesics - therapeutic use Cross-Sectional Studies Drug Prescriptions - statistics & numerical data Female Humans Iran - epidemiology Logistic Models Male Middle Aged Polypharmacy Potentially Inappropriate Medication List - statistics & numerical data Prevalence Risk Factors Socioeconomic Factors |
Title | Prevalence and associated factors of potentially inappropriate medications among Iranian older adults |
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