Fine epitope mapping of a human disulfide-stabilized diabody against fibroblast growth factor-2

The human fibroblast growth factor-2 (FGF-2) highly expressed in tumors is an important factor to promote tumor angiogenesis and lymphangiogensis. A disulfide-stabilized diabody (ds-Diabody) could specifically target FGF-2 and show its advantages in inhibition of tumor angiogenesis and growth. It is...

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Bibliographic Details
Published inJournal of biochemistry (Tokyo)
Main Authors Zhong, Jiangchuan, Zhang, Simin, Zhang, Ligang, Cai, Yaxiong, Deng, Yanrui, Zheng, Qubo, Deng, Ning
Format Journal Article
LanguageEnglish
Published England 31.12.2018
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