Low serum trough concentrations and high vancomycin MIC in methicillin-sensitive Staphylococcus aureus from hemodialysis patients in Brazil

• Published in: Therapeutic drug monitoring
• Main Authors: Penedo da Vitória, Michel, Alvarenga, Cristiane Gomes de Sousa, Vasconcellos Filho, Lauro Monteiro, Birro, Jéssica de Cássia Teixeira, Barbosa, Maralisi Coutinho, Ferreira, Mariana Abou Mourad, Schuenck, Ricardo Pinto, Ferreira Nunes, Ana Paula, Santos, Kênia Valéria Dos
• Format: Journal Article
• Language: English
• Published: United States 04.12.2018

The empiric antimicrobial therapy for bacteremia of long-term hemodialysis (HD) outpatients is currently based on the combination of vancomycin and gentamicin because of the high frequency of isolated Staphylococcus species. The vancomycin trough level range from 15 to 20 µg/mL is expected for thera...