Physiological Roles and Therapeutic Potential of Ca 2+ Activated Potassium Channels in the Nervous System

• Published in: Frontiers in molecular neuroscience Vol. 11; p. 258
• Main Authors: Kshatri, Aravind S, Gonzalez-Hernandez, Alberto, Giraldez, Teresa
• Format: Journal Article
• Language: English
• Published: Switzerland 2018
• Subjects: IK channels; nervous system; SK channels; drug discovery; neurological disease; BK channels; modulators

Within the potassium ion channel family, calcium activated potassium (K ) channels are unique in their ability to couple intracellular Ca signals to membrane potential variations. K channels are diversely distributed throughout the central nervous system and play fundamental roles ranging from regul...