In Vivo 1 H Magnetic Resonance Spectroscopy

In vivo Magnetic Resonance Spectroscopy (MRS) allows the non-invasive detection and quantification of a number of metabolites from localized volumes within a living organism. MRS localization techniques can be divided into two main groups, single voxel and multi-voxel. Single voxel techniques provid...

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Bibliographic Details
Published inMethods in molecular biology (Clifton, N.J.) Vol. 1718; p. 151
Main Authors Muñoz-Hernández, M Carmen, García-Martín, María Luisa
Format Journal Article
LanguageEnglish
Published United States 2018
Subjects
Animals
Brain - metabolism
Functional Neuroimaging - methods
Hydrogen - metabolism
Image Processing, Computer-Assisted - methods
Magnetic Resonance Imaging - methods
Proton Magnetic Resonance Spectroscopy - methods
Rodentia
Single voxel
Brain metabolites
Localized spectroscopy
1H MRS
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Summary:In vivo Magnetic Resonance Spectroscopy (MRS) allows the non-invasive detection and quantification of a number of metabolites from localized volumes within a living organism. MRS localization techniques can be divided into two main groups, single voxel and multi-voxel. Single voxel techniques provide the metabolic profile from a specific small volume, whereas multi-voxel techniques are used to obtain the spatial distribution of metabolites throughout a large volume subdivided into small contiguous voxels. This chapter describes standard protocols for the acquisition and processing of in vivo single voxel H MRS data from the rodent brain.
ISSN:1940-6029