Analysis of TCSPC data: a comparative evaluation of deterministic and probabilistic approaches

• Published in: Methods and applications in fluorescence
• Main Authors: Smith, Darren Andrew, McKenzie, Grant, Jones, Anita C, Smith, Trevor
• Format: Journal Article
• Language: English
• Published: England 18.07.2017
• Subjects: 2-Aminopurine; Exponential series method; Iterative reconvolution; Deterministic and probabilistic analysis; TCSPC; Basis pusuit denoising; Maximum entropy method

We review various methods for analysing time-resolved fluorescence data acquired using the time-correlated single photon counting (TCSPC) method in an attempt to evaluate their benefits and limitations. We have applied these methods to both experimental and simulated data. The relative merits of usi...