Genistein protects against Aβ 25-35 induced apoptosis of PC12 cells through JNK signaling and modulation of Bcl-2 family messengers
Deposition of aggregated amyloid beta (Aβ) protein is hallmark of Alzheimer's disease, leading to dysfunction and apoptosis of neurons. The isoflavone phytoestrogen compound genistein (Gen) exerts a significant protective effect against Aβ induced neurotoxicity and mitochondrial damage in rat p...
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Published in | BMC neuroscience Vol. 18; no. 1; p. 12 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
England
12.01.2017
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Subjects | |
Online Access | Get full text |
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