BIOELECTRIC ACTIVITY OF INTERNEURONES OF SPINAL CORD IN THE EXPERIMENTAL MENOPAUSE IN FEMAL RATS

• Published in: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Vol. 61; no. 5; p. 28
• Main Authors: Rodinsky, A G, Tkachenko, S S
• Format: Journal Article
• Language: Ukrainian
• Published: Ukraine 2015
• Subjects: Action Potentials - physiology; Animals; Electric Stimulation; Female; Ganglia, Spinal - cytology; Ganglia, Spinal - physiology; Interneurons - cytology; Interneurons - physiology; Menopause - physiology; Ovariectomy; Rats; Rats, Wistar; Spinal Cord - cytology; Spinal Cord - physiology
• ISSN: 2522-9028

We analyzed the amplitude-time characteristics of the components of the potential dorsal surface of the spinal cord (PDS SC) in experimental menopause. The excitation threshold increased at 102.14% and the latent period at 94.12% in animals with experimental menopause. In the context of supramaximal stimulation of dorsal root L5 identified N1 amplitude growth at 10.14%, N2 at 11.82%, N3 at 48.28%, and P-wave 31.58% and to increase component N3 26.54% in the experimental group. At condition of paired stimulation pulses on the time interval from 2 to 3 ms there was a significant increase, and from 6 to 30 ms--a depression of N1-component of the second PDS SC in the group of animals with experimental menopause. Thus, our results suggest the presence of changes in nerve structures of the posterior horn of the spinal cord at conditions of estrogen deficiency.