HPV genotypes prevalence in México and worldwide detected by Linear Array

• Published in: Revista médica (Mexico : 1983) Vol. 53 Suppl 2; p. S122
• Main Authors: Flores-Miramontes, María G, Torres-Reyes, Luis A, Aguilar-Lemarroy, Adriana, Vallejo-Ruíz, Verónica, Piña-Sánchez, Patricia, Cortés-Gutiérrez, Elva, Reyes-Leyva, Julio, Jave-Suárez, Luis Felipe
• Format: Journal Article
• Language: Spanish
• Published: Mexico 2015
• Subjects: Cervical Intraepithelial Neoplasia - epidemiology; Cervical Intraepithelial Neoplasia - virology; DNA, Viral - analysis; Female; Genotype; Genotyping Techniques; Global Health; Human papillomavirus 16 - genetics; Human papillomavirus 16 - isolation & purification; Human papillomavirus 18 - genetics; Human papillomavirus 18 - isolation & purification; Humans; Mexico - epidemiology; Oligonucleotide Array Sequence Analysis; Papillomaviridae - genetics; Papillomaviridae - isolation & purification; Papillomavirus Infections - epidemiology; Papillomavirus Infections - virology; Prevalence; Squamous Intraepithelial Lesions of the Cervix - epidemiology; Squamous Intraepithelial Lesions of the Cervix - virology; Uterine Cervical Neoplasms - epidemiology; Uterine Cervical Neoplasms - virology; Papillomavirus; Cervical cancer; HPV
• ISSN: 0443-5117

Infection with human papillomavirus (HPV) is the main factor associated with the development of cervical cancer (CC). Knowing about the prevalence of HPVs at different stages in the development of CC is important for determining the HPV oncogenic risk, the development of screening strategies, the evaluation of prevention programs, and also for vaccine designing. This paper is a meta-analysis of HPV prevalence worldwide and in Mexico from studies using the Linear Array® HPV Genotyping Test as a diagnostic test (it is the commercial test that, up to date, identifies the largest number of HPV genotypes in a single sample) in DNA of cervical samples from women with normal cytology, with low grade squamous intraepithelial lesions (LGSIL), with high grade squamous intraepithelial lesions (HGSIL) and with CC. The most prevalent genotypes after HPV-16 and -18 in women with CC varies depending on geographic region, which supports the need to develop detection and prevention strategies according to the characteristics of the population.