Study on the effect of black cumin (Nigella sativa Linn.) on experimental renal ischemia-reperfusion injury in rats

• Published in: Acta cirurgica brasileira Vol. 30; no. 8; p. 542
• Main Author: Mousavi, Ghafour
• Format: Journal Article
• Language: English
• Published: Brazil 01.08.2015
• Subjects: Animals; Blood Urea Nitrogen; Creatinine - blood; Kidney - blood supply; Kidney - drug effects; Kidney Function Tests; Male; Malondialdehyde - analysis; Nigella sativa - chemistry; Oxidative Stress; Peroxidases - blood; Plant Preparations - pharmacology; Plant Preparations - therapeutic use; Random Allocation; Rats, Wistar; Reperfusion Injury - blood; Reperfusion Injury - prevention & control; Reproducibility of Results; Seeds - chemistry; Time Factors; Treatment Outcome; Uric Acid - blood

To evaluate the effect of Black cumin (Nigella sativa Linn.) pre-treatment on renal ischemia/reperfusion (I/R) induced injury in the rats. A total of 40 male Wistar rats were randomly allocated into five equal groups including Sham, I/R model and three I/R+ Black cumin (0.5, 1 and 2%)-treated groups...