Soluble fibrin and D-dimer at normal pregnancy and pregnancy with risk of miscarriage

• Published in: Ukrains'kyi biokhimichnyi zhurnal (1999 ) Vol. 78; no. 4; p. 120
• Main Authors: Lugovskoĭ, E V, Kolesnikova, I N, Lugovskaia, N E, Gritsenko, P G, Litvinova, L M, Gogolinskaia, G K, Liashko, E D, Kostiuchenko, E P, Golota, V Ia, Kurochka, V V, Komisarenko, S V
• Format: Journal Article
• Language: Russian
• Published: Ukraine 01.07.2006
• Subjects: Abortion, Threatened - blood; Adolescent; Adult; Antibodies, Monoclonal - immunology; Biomarkers - analysis; Chromatography, Affinity; Female; Fibrin - analysis; Fibrin - immunology; Fibrin Fibrinogen Degradation Products - analysis; Fibrin Fibrinogen Degradation Products - immunology; Gestational Age; Humans; Immunoenzyme Techniques - methods; Predictive Value of Tests; Pregnancy - blood; Reproducibility of Results; Sensitivity and Specificity; Solubility

ELISA for soluble fibrin (SF) quantification has been elaborated on the basis of our fibrin-specific monoclonal antibodies (mAb). Epitope for these mAb is localized in fibrin fragment Bbeta118-134. The method was used on the blood plasma of healthy pregnant women (control group) and pregnant women w...