Cerebral calcifications: a clue for a diagnostic process in a nonspecific clinical case

• Published in: Anales de medicina interna (Madrid, Spain : 1984) Vol. 23; no. 3; p. 127
• Main Authors: Benito Conejero, S, Díaz Espejo, C, López Domínguez, J M, Pujol de la Llave, E
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.03.2006
• Subjects: Adult; Brain Diseases - diagnostic imaging; Brain Diseases - etiology; Calcinosis - diagnostic imaging; Calcinosis - etiology; Celiac Disease - complications; Celiac Disease - diagnosis; Celiac Disease - diet therapy; Diarrhea - etiology; Female; Glutens - adverse effects; Humans; Migraine with Aura - etiology; Occipital Lobe - diagnostic imaging; Occipital Lobe - pathology; Radiography; Remission Induction; Syndrome
• ISSN: 0212-7199

Coeliac disease is a gluten sensitive enteropathy, autoimmune in origin, which has been traditionally regarded as a gastrointestinal disease. Years later it has been reported an extraintestinal affection. A huge number of neurological syndromes of unknown cause had been initially described in association with coeliac disease, with total or partial response to a gluten free-diet. A specific kind of occipital cerebral calcifications in relation to coeliac disease has been also described, and sometimes it means the existence of a syndrome called "Gobby's Syndrome". We show a patient with a mild unknown coeliac disease, a woman who had occipital cerebral calcifications in a TAC cerebral, which was made because of her intractable migraines and that it lead to the diagnosis. The migraine disappeared after a gluten free-diet, like similar cases reported by literature. The fact of existing neurological symptoms associated to coeliac diseases opens a therapeutic window of opportunity because they would respond to a gluten free-diet.