Treatment of chronic Chagas' disease with an association of nifurtimox and corticoid

• Published in: Revista da Sociedade Brasileira de Medicina Tropical Vol. 35; no. 6; p. 547
• Main Authors: Rassi, Anis, Amato Neto, Vicente, de Siqueira, Astolpho Ferraz, Ferriolli Filho, Francisco, Amato, Valdir Sabbaga, Rassi, Gustavo Gabriel, Rassi Junior, Anis
• Format: Journal Article
• Language: Portuguese
• Published: Brazil 01.11.2002
• Subjects: Adult; Animals; Betamethasone - therapeutic use; Chagas Disease - diagnosis; Chagas Disease - drug therapy; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Glucocorticoids - therapeutic use; Humans; Male; Middle Aged; Nifurtimox - therapeutic use; Treatment Outcome; Trypanocidal Agents - therapeutic use; Xenodiagnosis

Ten patients with chronic Chagas' disease were treated with nifurtimox (8-9 mg/kg/day) associated with betamethasone (9 mg/day initially and then gradually reduced) during 60 days, with one exception. It was intended to combine the respective anti-parasitic and anti-inflammatory actions of thes...