Chronic peripheral arterial occlusive disease, platelet glycoproteins GPIIb-IIIa and GP Ib-IX, plasma von Willebrand factor and plasma fibrinogen concentrations in patients with type 2 diabetes mellitus

• Published in: Polskie archiwum medycyny wewne̦trznej Vol. 103; no. 3-4; p. 139
• Main Authors: Gosk-Bierska, I, Adamiec, R, Doskocz, W, Ciosek, W
• Format: Journal Article
• Language: Polish
• Published: Poland 01.03.2000
• Subjects: Adult; Aged; Arteriosclerosis - blood; Arteriosclerosis - complications; Blood Platelets - metabolism; Chronic Disease; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Female; Fibrinogen - analysis; Humans; Male; Middle Aged; Platelet Glycoprotein GPIb-IX Complex - analysis; Platelet Glycoprotein GPIIb-IIIa Complex - analysis; von Willebrand Factor - analysis

Diabetes mellitus (DM) type 2 is a very strong risk factor for atherosclerosis. The final event of atherosclerosis is the vessels occlusion by platelet riche thrombus. Platelets adhesion and aggregation is mediated by interaction between platelets glycoproteins: GPIb-IX, GPIIb-IIIa and adhesive prot...