Enantioselective Separation and Determination of Citalopram Enantiomers in Pharmaceutical Dosage Form and Bulk Drug Using Experimental Design Approach on Chiralcel registered OC as a Chiral Stationary Phase

• Published in: Acta chromatographica Vol. 23; no. 3; pp. 389 - 401
• Main Authors: Semreen, M H, Aboul-Enein, HY
• Format: Journal Article
• Language: English
• Published: 01.09.2011

An enantioselective HPLC method was developed and validated for the separation and the estimation of citalopram (CIT) enantiomers in bulk drug and pharmaceutical preparations. The method was validated for its linearity (correlation coefficient = 0.9994 and 0.996 for S-(+)-enantiomer and R-(-)-enanti...