In Vitro and In Vivo Evaluation of Melanin-Binding Decapeptide 4B4 Radiolabeled with super(177)Lu, super(166)Ho, and super(153)Sm Radiolanthanides for the Purpose of Targeted Radionuclide Therapy of Melanoma

• Published in: Cancer biotherapy & radiopharmaceuticals Vol. 26; no. 5; pp. 547 - 556
• Main Authors: Ballard, B, Jiang, Z, Soil, CE, Revskaya, E, Cutler, C S, Dadachova, E, Francesconi, L C
• Format: Journal Article
• Language: English
• Published: 01.10.2011

Melanoma is a malignancy with increasing incidence. Although primary tumors that are localized to the skin can be successfully treated by surgical removal, there is no satisfactory treatment for metastatic melanoma, a condition that has currently an estimated 5-year survival of just 6%. During the l...