Human Talymphotropic virus antibody screening of blood donors: rates of falseapositive results and evaluation of a potential donor reentry algorithm

• Published in: Transfusion (Philadelphia, Pa.) Vol. 51; no. 4; pp. 692 - 701
• Main Authors: Stramer, Susan L, Notari IV, Edward P, Zou, Shimian, Krysztof, David E, Brodsky, Jaye P, Tegtmeier, Gary E, Dodd, Roger Y
• Format: Journal Article
• Language: English
• Published: 01.04.2011
• Subjects: Algorithms; Antibodies; Blood donors; Clinical trials; Data processing; Enzyme immunoassay; Human T-lymphotropic virus 1; Human T-lymphotropic virus 2; Infection; Reinstatement

BACKGROUND: Blood donor screening with enzyme immunoassays (EIAs) for antibodies to human T-lymphotropic virus (HTLV)-I, and later to HTLV-I/II, has led to the unnecessary deferral of tens of thousands of individuals. The licensure of the Abbott PRISM HTLV-I/HTLV-II chemiluminescent immunoassay (ChL...