AKAP79/150 Interacts with AC8 and Regulates Ca2+-dependent cAMP Synthesis in Pancreatic and Neuronal Systems<inline-graphic xlink:href="sbox.jpg"/>

• Published in: The Journal of biological chemistry Vol. 285; no. 6; pp. 20328 - 20342
• Main Authors: Willoughby, Debbie, Masada, Nanako, Wachten, Sebastian, Pagano, Mario, Halls, Michelle L, Everett, Katy L, Ciruela, Antonio, Cooper, Dermot MF
• Format: Journal Article
• Language: English
• Published: 21.04.2010

Protein kinase A anchoring proteins (AKAPs) provide the backbone for targeted multimolecular signaling complexes that serve to localize the activities of cAMP. Evidence is accumulating of direct associations between AKAPs and specific adenylyl cyclase (AC) isoforms to facilitate the actions of prote...