Interaction between activated chemokine receptor 1 and FceRI at membrane rafts promotes communication and F-actin-rich cytoneme extensions between mast cells

• Published in: International immunology Vol. 22; no. 2; pp. 113 - 128
• Main Authors: Fifadara, Nimita H, Beer, Freddy, Ono, Shoichiro, Ono, Santa J
• Format: Journal Article
• Language: English
• Published: 01.02.2010

Chemokines play important regulatory roles in immunity, but their contributions to mast cell function remain poorly understood. We examined the effects of FceRI-chemokine receptor (CCR) 1 co-stimulation on receptor localization and cellular morphology of bone marrow-derived mast cells. Whereas FceRI...