Association of PPARG2 Pro12Ala variant with larger body mass index in mestizo and Amerindian populations of Mexico

• Published in: Human biology Vol. 79; no. 5; pp. 111 - 119
• Main Authors: Canizales-Quinteros, S, Aguilar-Salinas, C A, Ortiz-López, M G, Rodríguez-Cruz, M, Villarreal-Molina, M T, Coral-Vázquez, R, Huertas-Vázquez, A, Hernández-Caballero, A, López-Alarcón, M, Brito-Zurita, O R, Domínguez-Banda, A, Martinez-Sánchez, L R, Cetina, T Canto-de, Vilchis-Dorantes, G, Rosas-Vargas, H, Granados-Silvestre, M A, Medeiros-Domingo, A, Menjivar, M, Tusié-Luna, M T
• Format: Journal Article
• Language: English
• Published: 01.02.2007
• Subjects: Body; Diabetes; Human biology; Mexico; Obesity; Population

Previous studies have sought to associate the Pro12Ala variant of the peroxisome proliferator-activated receptor [gamma]2 (PPARG2) gene with type 2 diabetes, insulin resistance, and obesity, with controversial results. We have determined the Pro12Ala variant frequency in 370 nondiabetic Mexican Mest...