Synthesis and antibacterial activity of N-[2-[5-(methylthio)thiophen-2- yl]-2-oxoethyl] and N-[2-[5-(methylthio)thiophen-2-yl]-2-(oxyimino)ethyl]pip derivatives

• Published in: Bioorganic & medicinal chemistry Vol. 14; no. 10; pp. 3421 - 3427
• Main Authors: oumadi, Alireza, Oboudiat, Mehdi, Emami, Saeed, Karimollah, Alireza, Saghaee, Lotfollah, Moshafi, Mohammad Hassan, Shafiee, Abbas
• Format: Journal Article
• Language: English
• Published: 01.01.2006
• Subjects: Staphylococcus aureus; Staphylococcus epidermidis

A number of N-substituted piperazinylquinolone derivatives were synthesized and evaluated for antibacterial activity against Gram-positive and Gram-negative bacteria. Preliminary results indicated that most compounds tested in this study demonstrated comparable or better activity against Staphylococ...