Blockade of purinergic 2 receptors attenuates the mechanoreceptor component of the exercise pressor reflex

• Published in: American Journal of Physiology: Cell Physiology Vol. 293; no. 5; pp. H2995 - H3000
• Main Authors: Kindig, Angela E, Hayes, Shawn G, Kaufman, Marc P
• Format: Journal Article
• Language: English
• Published: 01.11.2007

The finding that pyridoxalphosphate-6-azophenyl-2,4-disulfonic acid (PPADS), a P2 antagonist, attenuated the pressor response to calcaneal tendon stretch, a purely mechanical stimulus, raises the possibility that P2 receptors sensitize mechanoreceptors to static contraction of the triceps surae musc...