beta 1-subunit-induced structural rearrangements of the Ca super( 2+)- and voltage-activated K+ (BK) channel

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 113; no. 23; p. E3231
• Main Authors: Castillo, Juan P, Sanchez-Rodriguez, Jorge E, Hyde, H Clark, Zaelzer, Cristian A, Aguayo, Daniel, Sepulveda, Romina V, Luk, Louis YP, Kent, Stephen BH, Gonzalez-Nilo, Fernando D, Bezanilla, Francisco, Latorre, Ramon
• Format: Journal Article
• Language: English
• Published: 01.06.2016

Large-conductance Ca super( 2+)- and voltage-activated K super( +) (BK) channels are involved in a large variety of physiological processes. Regulatory beta -subunits are one of the mechanisms responsible for creating BK channel diversity fundamental to the adequate function of many tissues. However...