HOR7, a Multicopy Suppressor of the Ca super(2+)-induced Growth Defect in Sphingolipid Mannosyltransferase-deficient Yeast

• Published in: The Journal of biological chemistry Vol. 279; no. 35; pp. 36390 - 36396
• Main Authors: Lisman, Quirine, Urli-Stam, Dorothy, Holthuis, Joost CM
• Format: Journal Article
• Language: English
• Published: 27.08.2004
• Subjects: Saccharomyces cerevisiae

Yeast mutants defective in sphingolipid mannosylation accumulate inositol phosphorylceramide C (IPC-C), which renders cells Ca super(2+)-sensitive. A screen for loss of function suppressors of the Ca super(2+)-sensitive phenotype previously led to the identification of numerous genes involved in IPC...