Synthesis of Pyrrolidine Derivatives by a Platinum/Broensted Acid Relay Catalytic Cascade Reaction

• Published in: Chemistry : a European journal Vol. 21; no. 8; pp. 3409 - 3414
• Main Authors: Galvan, Alicia, Calleja, Jonas, Fananas, Francisco J, Rodriguez, Felix
• Format: Journal Article
• Language: English
• Published: 01.02.2015
• Subjects: Alkenes; Alkynes; Catalysis; Catalysts; Derivatives; Platinum; Synthesis (chemistry); Triflic acid

A new catalytic reaction for the synthesis of pyrrolidine derivatives is presented. The method implies the coupling of N-Boc-protected alkynamine derivatives and appropriate alkenes or alkynes in a process catalysed by a platinum/triflic acid catalytic binary system. This reaction is believed to pro...